A 28-year-old previously healthy outpatient with fever, cough, and lobar infiltrate on CXR has no comorbidities and no recent antibiotics. Macrolide r...

Question

A 28-year-old previously healthy outpatient with fever, cough, and lobar infiltrate on CXR has no comorbidities and no recent antibiotics. Macrolide resistance in the community is >25%. Best empiric oral therapy?

Accepted Answer

Amoxicillin 1 g three times daily for 5 days

Answer

Azithromycin monotherapy for 5 days

Answer

Levofloxacin 750 mg daily for 5 days

Answer

Cefuroxime 500 mg twice daily plus doxycycline 100 mg twice daily

Answer

Trimethoprim-sulfamethoxazole twice daily for 7 days

us-abfm MCQ (SBA): Community-Acquired Pneumonia

A 28-year-old previously healthy outpatient with fever, cough, and lobar infiltrate on CXR has no comorbidities and no recent antibiotics. Macrolide resistance in the community is >25%. Best empiric oral therapy?