Question

A 65-year-old with chronic AF (CHA2DS2-VASc 4) is started on apixaban and asks about renal dosing as eGFR declines. Which is correct?

Accepted Answer

Dose adjustment based on age ≥80, weight ≤60 kg, and creatinine ≥1.5; not purely on eGFR

Answer

Always reduce dose if eGFR <60

Answer

Never reduce dose

Answer

Switch to warfarin at eGFR 50

Answer

Use once-daily dosing

Practice question

A 65-year-old with chronic AF (CHA2DS2-VASc 4) is started on apixaban and asks about renal dosing as eGFR declines. Which is correct?