A 62-year-old with A1C 8.9% and symptomatic heart failure asks about pioglitazone. What should you advise?...

Question

A 62-year-old with A1C 8.9% and symptomatic heart failure asks about pioglitazone. What should you advise?

Accepted Answer

Avoid TZDs in symptomatic HF due to fluid retention

Answer

Start TZD; HF improves

Answer

TZDs are first-line in HF

Answer

Use high-dose TZD with diuretics

Answer

TZDs have no fluid effects

us-abfm MCQ (SBA): TZDs and Heart Failure