Question

A 54-year-old with new-onset severe community-acquired C. difficile on CT (pancolitis), WBC 17,500, Cr 1.3. No shock. Best initial antibiotic?

Accepted Answer

Fidaxomicin or oral vancomycin (no metronidazole monotherapy)

Answer

Metronidazole alone

Answer

Probiotics alone

Answer

IV vancomycin

Answer

Rifaximin monotherapy

Practice question

A 54-year-old with new-onset severe community-acquired C. difficile on CT (pancolitis), WBC 17,500, Cr 1.3. No shock. Best initial antibiotic?