Question

A 72-year-old with obesity, CKD stage 3, and hypertension develops symptomatic COVID-19 (day 3). eGFR 55 mL/min; no major drug interactions. Best outpatient therapy?

Accepted Answer

Start nirmatrelvir/ritonavir within 5 days of symptom onset

Answer

Start oseltamivir

Answer

No antivirals; observe only

Answer

Start dexamethasone 6 mg daily as outpatient

Answer

Start molnupiravir as first-line despite eligibility for others

Practice question

A 72-year-old with obesity, CKD stage 3, and hypertension develops symptomatic COVID-19 (day 3). eGFR 55 mL/min; no major drug interactions. Best outpatient therapy?