Question

A 70-year-old with HFrEF on optimal therapy has symptomatic hypotension after starting sacubitril/valsartan 24/26 mg BID 36 hours after stopping lisinopril. Which action is most appropriate?

Accepted Answer

Reduce ARNI dose and reassess volume status

Answer

Stop ARNI and restart ACE inhibitor immediately

Answer

Add hydralazine/isosorbide dinitrate immediately

Answer

Stop beta-blocker

Answer

Continue ARNI and double diuretic

Practice question

A 70-year-old with HFrEF on optimal therapy has symptomatic hypotension after starting sacubitril/valsartan 24/26 mg BID 36 hours after stopping lisinopril. Which action is most appropriate?