A 58-year-old woman presents with persistent atrial fibrillation and heart failure symptoms despite optimal rate control. Rhythm control is being considered. Which of the following statements is true? A Antiarrhythmic drugs are preferred in all patients with persistent atrial fibrillation and heart failure. B Catheter ablation is a reasonable strategy to improve symptoms and outcomes in selected patients with heart failure with reduced ejection fraction (HFrEF). C Rhythm control strategies never improve outcomes in patients with atrial fibrillation. D Atrioventricular (AV) nodal ablation is the first-line treatment for rhythm control in patients with atrial fibrillation and heart failure. E Dofetilide should always be avoided in patients with HFrEF.
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