Question

A 58-year-old with obesity and gout presents with acute monoarthritis (onset 12 hours). He has CKD stage 3b. Best acute gout therapy?

Accepted Answer

Colchicine low-dose regimen (1.2 mg then 0.6 mg 1 h later)

Answer

High-dose colchicine until diarrhea

Answer

Indomethacin 50 mg tid regardless of CKD

Answer

Allopurinol initiation now without anti-inflammatory prophylaxis

Answer

Intra-articular glucocorticoid for any joint size is contraindicated

Practice question

A 58-year-old with obesity and gout presents with acute monoarthritis (onset 12 hours). He has CKD stage 3b. Best acute gout therapy?