A 64-year-old woman with AF on apixaban needs elective knee arthroplasty (high bleeding risk). eGFR 65. What perioperative management is recommended?...

Question

A 64-year-old woman with AF on apixaban needs elective knee arthroplasty (high bleeding risk). eGFR 65. What perioperative management is recommended?

Accepted Answer

Hold apixaban ~48-72 hours pre-op; no heparin bridging

Answer

Hold morning dose only; bridge with LMWH

Answer

Continue apixaban through surgery

Answer

Switch to warfarin, bridge with UFH

Answer

Hold apixaban 7 days

us-abim MCQ (SBA): Perioperative Anticoagulation