A 58-year-old with suspected HAP in the ICU is started on vancomycin + piperacillin-tazobactam + amikacin. Cultures return MSSA, Pseudomonas absent. B...

Question

A 58-year-old with suspected HAP in the ICU is started on vancomycin + piperacillin-tazobactam + amikacin. Cultures return MSSA, Pseudomonas absent. Best next step?

Accepted Answer

De-escalate to a single antistaphylococcal agent targeting MSSA

Answer

Continue triple therapy for full course

Answer

Switch to doxycycline

Answer

Stop all antibiotics immediately

Answer

Add antifungal coverage

us-abim MCQ (SBA): HAP/VAP

A 58-year-old with suspected HAP in the ICU is started on vancomycin + piperacillin-tazobactam + amikacin. Cultures return MSSA, Pseudomonas absent. Best next step?