Question

A 63-year-old with nonvalvular AF and eGFR 35 mL/min/1.73 m² needs anticoagulation. Which DOAC is appropriate at standard dosing?

Accepted Answer

Apixaban 5 mg twice daily (dose-reduce only if 2 of: age ≥80, weight ≤60 kg, creatinine ≥1.5)

Answer

Rivaroxaban 20 mg daily without renal adjustment

Answer

Dabigatran 150 mg bid without adjustment at this eGFR

Answer

Edoxaban 60 mg daily universally

Answer

No anticoagulation

Practice question

A 63-year-old with nonvalvular AF and eGFR 35 mL/min/1.73 m² needs anticoagulation. Which DOAC is appropriate at standard dosing?