A 58-year-old with chronic HCV (genotype unknown), no cirrhosis, and normal renal function seeks treatment. Which approach aligns with simplified ther...

Question

A 58-year-old with chronic HCV (genotype unknown), no cirrhosis, and normal renal function seeks treatment. Which approach aligns with simplified therapy?

Accepted Answer

Offer pangenotypic DAA (e.g., glecaprevir/pibrentasvir 8 weeks) after staging and drug-drug review

Answer

Delay treatment pending genotype only

Answer

Interferon and ribavirin for 24-48 weeks

Answer

No treatment until ALT >3x ULN

Answer

Liver biopsy mandatory before therapy

us-abim MCQ (SBA): Chronic Hepatitis C

A 58-year-old with chronic HCV (genotype unknown), no cirrhosis, and normal renal function seeks treatment. Which approach aligns with simplified therapy?