Question

A 42-year-old with watery diarrhea 8 times/day 2 days after finishing clindamycin tests positive for C. difficile (first episode). Best initial therapy?

Accepted Answer

Fidaxomicin 200 mg orally twice daily for 10 days

Answer

Metronidazole 500 mg orally TID x10 days as preferred

Answer

Vancomycin enemas

Answer

Do not treat unless WBC >15,000/µL

Answer

Probiotics alone

Practice question

A 42-year-old with watery diarrhea 8 times/day 2 days after finishing clindamycin tests positive for C. difficile (first episode). Best initial therapy?