Question

A 72-year-old man with AF on apixaban needs urgent surgery in 12 hours. CrCl 25 mL/min. What is the best approach?

Accepted Answer

Consider delaying if possible; if not, proceed with bleeding risk mitigation and reversal strategies as appropriate

Answer

Bridge with LMWH

Answer

Switch to warfarin overnight

Answer

No adjustments needed

Answer

Start aspirin to offset DOAC

Practice question

A 72-year-old man with AF on apixaban needs urgent surgery in 12 hours. CrCl 25 mL/min. What is the best approach?