Question

A 55-year-old with dysuria and flank pain has pyelonephritis. Urine culture pending; local E. coli fluoroquinolone resistance is >10%. Appropriate empiric outpatient therapy?

Accepted Answer

Initial parenteral long-acting agent (e.g., ceftriaxone) then oral based on susceptibilities

Answer

Oral ciprofloxacin regardless of resistance

Answer

Nitrofurantoin

Answer

No antibiotics until culture

Answer

Amoxicillin alone

Practice question

A 55-year-old with dysuria and flank pain has pyelonephritis. Urine culture pending; local E. coli fluoroquinolone resistance is >10%. Appropriate empiric outpatient therapy?