Question

A 60-year-old with gout and CKD stage 3 starts urate-lowering therapy. Which is preferred first-line with treat-to-target strategy?

Accepted Answer

Allopurinol titrated to serum urate <6 mg/dL

Answer

Febuxostat first-line for all

Answer

Probenecid first-line in CKD

Answer

Stop therapy once urate reaches 6.5 mg/dL

Answer

Start high-dose allopurinol 600 mg/day initially

Practice question

A 60-year-old with gout and CKD stage 3 starts urate-lowering therapy. Which is preferred first-line with treat-to-target strategy?