Question

A 66-year-old with NSTEMI underwent PCI with a drug-eluting stent and now needs oral anticoagulation for atrial fibrillation (CHA₂DS₂-VASc 4). Which regimen minimizes bleeding while maintaining efficacy after discharge (no high bleeding risk, uncomplicated PCI)?

Accepted Answer

DOAC + clopidogrel; stop aspirin at discharge

Answer

Triple therapy (DOAC + aspirin + clopidogrel) for 12 months

Answer

Warfarin + aspirin for 12 months

Answer

DOAC alone without antiplatelet therapy for 12 months

Answer

Warfarin + clopidogrel + aspirin for 1 month then warfarin alone

Practice question

A 66-year-old with NSTEMI underwent PCI with a drug-eluting stent and now needs oral anticoagulation for atrial fibrillation (CHA₂DS₂-VASc 4). Which regimen minimizes bleeding while maintaining efficacy after discharge (no high bleeding risk, uncomplicated PCI)?