Question

A hospitalized adult has first-episode, nonsevere Clostridioides difficile infection (WBC 13,000/µL, creatinine 1.0 mg/dL). Which initial therapy is preferred?

Accepted Answer

Fidaxomicin 200 mg orally twice daily for 10 days

Answer

Oral metronidazole 500 mg three times daily for 10 days

Answer

Oral vancomycin 125 mg four times daily for 10 days

Answer

Loperamide to reduce stool output

Answer

Intravenous tigecycline

Practice question

A hospitalized adult has first-episode, nonsevere Clostridioides difficile infection (WBC 13,000/µL, creatinine 1.0 mg/dL). Which initial therapy is preferred?