Question

A 48-year-old with gout and serum urate 8.6 mg/dL has ≥2 flares/year and tophus. eGFR 55. Best long-term therapy?

Accepted Answer

Allopurinol with treat-to-target <6 mg/dL, with flare prophylaxis

Answer

Probenecid

Answer

NSAIDs PRN only

Answer

Colchicine only for flares

Answer

Febuxostat only if CKD stage ≥3

Practice question

A 48-year-old with gout and serum urate 8.6 mg/dL has ≥2 flares/year and tophus. eGFR 55. Best long-term therapy?