Question

A 64-year-old with nonvalvular AF on apixaban 5 mg twice daily is scheduled for elective colon cancer resection (high bleeding risk). Renal function is normal. Perioperative DOAC plan?

Accepted Answer

Hold apixaban 48 hours before and restart ~48 hours after surgery

Answer

Continue apixaban through surgery

Answer

Hold apixaban 24 hours pre-op only

Answer

Bridge with LMWH after stopping apixaban

Answer

Switch to warfarin one week before

Practice question

A 64-year-old with nonvalvular AF on apixaban 5 mg twice daily is scheduled for elective colon cancer resection (high bleeding risk). Renal function is normal. Perioperative DOAC plan?