A 52-year-old man with back pain and fever is found to have pyelonephritis. He is stable for outpatient therapy and local resistance to fluoroquinolon...

Question

A 52-year-old man with back pain and fever is found to have pyelonephritis. He is stable for outpatient therapy and local resistance to fluoroquinolones is high. Best empiric choice?

Accepted Answer

Initial parenteral long-acting agent (e.g., ceftriaxone) then appropriate oral based on susceptibilities

Answer

TMP-SMX empirically despite resistance

Answer

Oral nitrofurantoin

Answer

No antibiotics

Answer

Oral amoxicillin alone

us-abfm MCQ (SBA): Pyelonephritis Outpatient Management

A 52-year-old man with back pain and fever is found to have pyelonephritis. He is stable for outpatient therapy and local resistance to fluoroquinolones is high. Best empiric choice?