A 43-year-old with watery diarrhea 8 times/day, WBC 15,000, creatinine 1.1, stool toxin positive for C. difficile. First episode, no fulminant disease...

Question

A 43-year-old with watery diarrhea 8 times/day, WBC 15,000, creatinine 1.1, stool toxin positive for C. difficile. First episode, no fulminant disease. Best initial therapy?

Accepted Answer

Fidaxomicin 200 mg orally twice daily for 10 days

Answer

Oral vancomycin 125 mg every 6 hours for 10 days as first choice

Answer

Metronidazole 500 mg orally three times daily for 10 days

Answer

Probiotics alone

Answer

Bezlotoxumab monotherapy

us-abim MCQ (SBA): Clostridioides difficile Infection

A 43-year-old with watery diarrhea 8 times/day, WBC 15,000, creatinine 1.1, stool toxin positive for C. difficile. First episode, no fulminant disease. Best initial therapy?