Question

A 65-year-old man with HFrEF (LVEF 30%) on lisinopril and metoprolol succinate is euvolemic (BP 122/76, K+ 4.6, eGFR 65 mL/min/1.73 m²). Which additional therapy provides mortality benefit and should be added now?

Accepted Answer

Dapagliflozin 10 mg daily

Answer

Furosemide 40 mg daily

Answer

Ivabradine 7.5 mg twice daily

Answer

Digoxin 0.125 mg daily

Answer

Hydralazine 50 mg + isosorbide dinitrate 30 mg three times daily (in non-Black patient)

Practice question

A 65-year-old man with HFrEF (LVEF 30%) on lisinopril and metoprolol succinate is euvolemic (BP 122/76, K+ 4.6, eGFR 65 mL/min/1.73 m²). Which additional therapy provides mortality benefit and should be added now?