Question

A 67-year-old postmenopausal woman has a DEXA scan showing a T-score of -2.7 at the femoral neck. She has no history of fragility fractures but has a FRAX 10-year probability of major osteoporotic fracture of 25%. What is the most appropriate pharmacologic management?

Accepted Answer

Begin bisphosphonate therapy.

Answer

Reassure and repeat DEXA in 5 years without treatment.

Answer

Start calcium and vitamin D supplementation only.

Answer

Begin long-term systemic glucocorticoids.

Answer

Recommend hormone replacement therapy in all such women.

Practice question

A 67-year-old postmenopausal woman has a DEXA scan showing a T-score of -2.7 at the femoral neck. She has no history of fragility fractures but has a FRAX 10-year probability of major osteoporotic fracture of 25%. What is the most appropriate pharmacologic management?