Question

A 70-year-old woman with atrial fibrillation on warfarin therapy presents with severe headache and confusion. CT head shows a large intracerebral hemorrhage. Her INR is 3.5. Which is the most appropriate immediate management for anticoagulation reversal?

Accepted Answer

Administer intravenous vitamin K and 4-factor prothrombin complex concentrate

Answer

Vitamin K orally only

Answer

Stop warfarin and observe

Answer

Administer fresh frozen plasma alone

Answer

Switch to a direct oral anticoagulant immediately

Practice question

A 70-year-old woman with atrial fibrillation on warfarin therapy presents with severe headache and confusion. CT head shows a large intracerebral hemorrhage. Her INR is 3.5. Which is the most appropriate immediate management for anticoagulation reversal?