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EasyPsychiatryMajor depressive disorderus-abfmus-abimus-usmle-step-2

A 45-year-old woman presents with fatigue, low mood, and anhedonia for 4 months. She has difficulty sleeping and concentrating and feels guilty most days. She denies suicidal ideation. There is no history of mania or hypomania. Which treatment is most appropriate as initial pharmacotherapy?

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