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HardGastroenterologyPrimary biliary cholangitisus-abimus-usmle-step-2us-usmle-step-3

A 46-year-old woman presents with fatigue, pruritus, and jaundice. Laboratory tests show elevated alkaline phosphatase and gamma-glutamyl transferase with mildly elevated AST and ALT. Anti-mitochondrial antibody is positive. What is the most appropriate initial treatment?

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