Question

A 58-year-old woman with community-acquired pneumonia is started empirically on ceftriaxone plus azithromycin. MRSA nasal PCR is negative; no risk factors. De-escalation after cultures negative at 48 hours?

Accepted Answer

Narrow to ceftriaxone monotherapy

Answer

Continue MRSA coverage for 7 days

Answer

Add vancomycin

Answer

Stop atypical coverage immediately

Answer

Switch to piperacillin-tazobactam

Practice question

A 58-year-old woman with community-acquired pneumonia is started empirically on ceftriaxone plus azithromycin. MRSA nasal PCR is negative; no risk factors. De-escalation after cultures negative at 48 hours?