A 73-year-old man with AF on apixaban presents for urgent hip fracture repair. Last dose was 18 hours ago; CrCl 45 mL/min. What is recommended?...

Question

A 73-year-old man with AF on apixaban presents for urgent hip fracture repair. Last dose was 18 hours ago; CrCl 45 mL/min. What is recommended?

Accepted Answer

Delay surgery until 48-72 hours after last dose if feasible

Answer

Bridge with IV heparin then operate now

Answer

Give vitamin K to reverse apixaban

Answer

Give protamine to reverse apixaban

Answer

Operate immediately without considering anticoagulant timing

us-abem MCQ (SBA): Perioperative DOAC Management