Question

A 72-year-old man with persistent nonvalvular atrial fibrillation, hypertension, diabetes, and eGFR 45 mL/min/1.73 m^2 has a CHA2DS2-VASc score of 4. He has no mechanical valve and no moderate-to-severe mitral stenosis. What is the preferred oral anticoagulant strategy for stroke prevention?

Accepted Answer

Apixaban standard dosing adjusted for renal function

Answer

Warfarin targeting INR 2-3

Answer

Aspirin 81 mg daily

Answer

Clopidogrel 75 mg daily

Answer

No anticoagulation because eGFR <60

Practice question

A 72-year-old man with persistent nonvalvular atrial fibrillation, hypertension, diabetes, and eGFR 45 mL/min/1.73 m^2 has a CHA2DS2-VASc score of 4. He has no mechanical valve and no moderate-to-severe mitral stenosis. What is the preferred oral anticoagulant strategy for stroke prevention?