A 28-year-old with acute gout flare and stage 3 CKD needs urate-lowering therapy. Preferred first-line ULT and starting dose?...

Question

A 28-year-old with acute gout flare and stage 3 CKD needs urate-lowering therapy. Preferred first-line ULT and starting dose?

Accepted Answer

Allopurinol

Answer

Febuxostat 80 mg daily

Answer

Probenecid 500 mg bid

Answer

Pegloticase IV every 2 weeks

Answer

No ULT until >=3 flares/year

us-abfm MCQ (SBA): Gout