A 50-year-old woman with suspected stroke is on a factor Xa inhibitor (last dose 5 hours ago). She presents 1.5 hours after onset of disabling deficit...

Question

A 50-year-old woman with suspected stroke is on a factor Xa inhibitor (last dose 5 hours ago). She presents 1.5 hours after onset of disabling deficits. Which statement is correct?

Accepted Answer

IV alteplase is contraindicated if a DOAC was taken within 48 hours (and anticoagulant effect persists)

Answer

Proceed with alteplase regardless of DOAC

Answer

Wait 24 hours and give tenecteplase

Answer

Give heparin instead of thrombolysis

Answer

Administer PCC then alteplase immediately

us-abem MCQ (SBA): AIS Thrombolysis and DOACs

A 50-year-old woman with suspected stroke is on a factor Xa inhibitor (last dose 5 hours ago). She presents 1.5 hours after onset of disabling deficits. Which statement is correct?