A 28-year-old woman with newly diagnosed type 2 diabetes mellitus has an A1C of 10.8% and fasting glucose 320 mg/dL. She has polyuria, polydipsia, and...

Question

A 28-year-old woman with newly diagnosed type 2 diabetes mellitus has an A1C of 10.8% and fasting glucose 320 mg/dL. She has polyuria, polydipsia, and 10-pound unintentional weight loss over 3 months. There is no ketoacidosis. What is the most appropriate initial pharmacologic treatment?

Accepted Answer

Delay pharmacologic therapy and focus on lifestyle modification only

Answer

Start metformin monotherapy

Answer

Start basal-bolus insulin therapy

Answer

Start a sulfonylurea alone

Answer

Start an SGLT2 inhibitor alone

us-abfm MCQ (SBA): Severe Hyperglycemia in Type 2 Diabetes

A 28-year-old woman with newly diagnosed type 2 diabetes mellitus has an A1C of 10.8% and fasting glucose 320 mg/dL. She has polyuria, polydipsia, and 10-pound unintentional weight loss over 3 months. There is no ketoacidosis. What is the most appropriate initial pharmacologic treatment?