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EasyPsychiatryMajor Depressive Disorderus-abfmus-abimus-usmle-step-2us-usmle-step-3

A 42-year-old man with no significant past medical history presents with low mood, anhedonia, poor concentration, early morning awakening, and feelings of worthlessness for 6 weeks. He denies suicidality or psychotic symptoms and continues to work but with difficulty. Which is the most appropriate initial treatment?

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