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Moderate"A"Rapid initiation and up-titration of the four foundational HFrEF therapies within weeks to improve outcomes. Delaying therapy or avoiding MRA without indication is inappropriate."aha/acc/hfsa guideline (2022): management of heart failure"

A 62-year-old with prior MI and new HFrEF (LVEF 30%) is euvolemic. Which sequence reflects rapid optimization of GDMT?

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