A 66-year-old with AF and CKD G3a (eGFR 52) on apixaban 5 mg twice daily is admitted for pneumonia. Weight 61 kg, age 66, creatinine 1.6 mg/dL. Should...

Question

A 66-year-old with AF and CKD G3a (eGFR 52) on apixaban 5 mg twice daily is admitted for pneumonia. Weight 61 kg, age 66, creatinine 1.6 mg/dL. Should the apixaban dose be adjusted?

Accepted Answer

Continue 5 mg bid because dose-reduction criteria are not met

Answer

Reduce to 2.5 mg bid because age >65

Answer

Reduce to 2.5 mg bid because creatinine >=1.5 and weight

Answer

Stop apixaban and use warfarin

Answer

Use once-daily dosing

us-abim MCQ (SBA): AF (Apixaban Dosing)

A 66-year-old with AF and CKD G3a (eGFR 52) on apixaban 5 mg twice daily is admitted for pneumonia. Weight 61 kg, age 66, creatinine 1.6 mg/dL. Should the apixaban dose be adjusted?