Question

A 68-year-old woman with GERD controlled on daily PPI and osteoporosis on alendronate asks about long-term PPI safety. What is evidence-based management?

Accepted Answer

Use lowest effective PPI dose; reassess necessity; ensure appropriate osteoporosis management

Answer

Stop PPI regardless of symptoms

Answer

Switch to H2 blocker regardless of efficacy

Answer

Add sucralfate long-term

Answer

Increase PPI dose to BID to prevent complications

Practice question

A 68-year-old woman with GERD controlled on daily PPI and osteoporosis on alendronate asks about long-term PPI safety. What is evidence-based management?