Question

A 61-year-old hospitalized with nonsevere initial Clostridioides difficile infection (WBC 10,200/µL, creatinine 1.1 mg/dL) has first episode. What is the preferred initial therapy?

Accepted Answer

Fidaxomicin 200 mg PO BID for 10 days

Answer

Metronidazole 500 mg PO TID for 10 days

Answer

Vancomycin 250 mg PO QID plus IV metronidazole

Answer

Vancomycin 125 mg PO QID for 14 days then taper

Answer

Probiotics alone

Practice question

A 61-year-old hospitalized with nonsevere initial Clostridioides difficile infection (WBC 10,200/µL, creatinine 1.1 mg/dL) has first episode. What is the preferred initial therapy?