A 47-year-old hospitalized patient with watery diarrhea after 7 days of antibiotics has WBC 12,000/μL, creatinine normal, and positive NAAT for toxin ...

Question

A 47-year-old hospitalized patient with watery diarrhea after 7 days of antibiotics has WBC 12,000/μL, creatinine normal, and positive NAAT for toxin genes with toxin EIA positive. What is preferred initial therapy?

Accepted Answer

Oral vancomycin 125 mg QID for 10 days or fidaxomicin 200 mg BID for 10 days, with fidaxomicin preferred

Answer

Oral metronidazole 500 mg TID for 10 days

Answer

Stop antibiotics only; no specific therapy needed

Answer

Probiotics as sole therapy

Answer

IV vancomycin

us-abim MCQ (SBA): Clostridioides difficile Infection

A 47-year-old hospitalized patient with watery diarrhea after 7 days of antibiotics has WBC 12,000/μL, creatinine normal, and positive NAAT for toxin genes with toxin EIA positive. What is preferred initial therapy?