Question

A 24-year-old with watery diarrhea after clindamycin has a first episode of nonsevere C. difficile infection (WBC 9,000/µL, creatinine normal). Optimal initial therapy?

Accepted Answer

Fidaxomicin 200 mg orally twice daily for 10 days

Answer

Metronidazole 500 mg orally three times daily for 10 days

Answer

Vancomycin 125 mg orally four times daily for 10 days plus IV metronidazole

Answer

Probiotics alone

Answer

No antibiotics; observe

Practice question

A 24-year-old with watery diarrhea after clindamycin has a first episode of nonsevere C. difficile infection (WBC 9,000/µL, creatinine normal). Optimal initial therapy?