A 57-year-old woman with gout and tophaceous deposits has had 3 flares this year. Serum urate 8.2 mg/dL. Best disease-modifying intervention?...

Question

A 57-year-old woman with gout and tophaceous deposits has had 3 flares this year. Serum urate 8.2 mg/dL. Best disease-modifying intervention?

Accepted Answer

PRN colchicine only

Answer

Probenecid first-line

Answer

Start allopurinol and titrate to serum urate

Answer

Stop thiazide and reassess in 1 year

Answer

Febuxostat only if CKD stage 4

us-abfm MCQ (SBA): Gout