A 68-year-old with severe COPD exacerbation and suspected bacterial infection meets Anthonisen criteria (increased dyspnea, sputum purulence and volume). Which antibiotic approach is reasonable?ANo antibiotics regardless of sputumBMacrolide only if eosinophils highCAntibiotics indicated when all three cardinal symptoms are present or if mechanical ventilation is requiredDReserve antibiotics only for radiographic pneumoniaETreat with IV vancomycin empiricallyCheck my answer