Question

A 69-year-old hospitalized patient has first episode, nonsevere Clostridioides difficile infection (WBC 10,500/µL; creatinine 0.9 mg/dL). Best initial therapy?

Accepted Answer

Fidaxomicin 200 mg orally BID for 10 days

Answer

Metronidazole 500 mg orally TID for 10 days

Answer

Vancomycin 125 mg orally QID for 10 days

Answer

Tigecycline IV

Answer

Bezlotoxumab monotherapy

Practice question

A 69-year-old hospitalized patient has first episode, nonsevere Clostridioides difficile infection (WBC 10,500/µL; creatinine 0.9 mg/dL). Best initial therapy?