Question

A 68-year-old develops a first episode of non-severe Clostridioides difficile infection (WBC 11,000/µL; creatinine 1.1 mg/dL). Which initial therapy is preferred?

Accepted Answer

Fidaxomicin 200 mg orally twice daily for 10 days

Answer

Metronidazole 500 mg orally three times daily for 10 days

Answer

Vancomycin 125 mg orally four times daily only if fidaxomicin fails

Answer

No antibiotic; probiotics alone

Answer

IV vancomycin 1 g twice daily

Practice question

A 68-year-old develops a first episode of non-severe Clostridioides difficile infection (WBC 11,000/µL; creatinine 1.1 mg/dL). Which initial therapy is preferred?