A 28-year-old develops severe anaphylaxis 10 minutes after ingesting peanuts. He has stridor, diffuse urticaria, wheeze, vomiting, and hypotension (BP...

Question

A 28-year-old develops severe anaphylaxis 10 minutes after ingesting peanuts. He has stridor, diffuse urticaria, wheeze, vomiting, and hypotension (BP 78/50 mm Hg; SpO2 88% on room air). What is the most appropriate immediate treatment?

Accepted Answer

Intramuscular epinephrine 0.3-0.5 mg (1 mg/mL) into the mid-anterolateral thigh now

Answer

Intravenous diphenhydramine 50 mg now

Answer

Albuterol-ipratropium nebulization with methylprednisolone 125 mg IV

Answer

Begin epinephrine infusion only after central venous access

Answer

Normal saline bolus only, then observe

us-abem MCQ (SBA): Anaphylaxis

A 28-year-old develops severe anaphylaxis 10 minutes after ingesting peanuts. He has stridor, diffuse urticaria, wheeze, vomiting, and hypotension (BP 78/50 mm Hg; SpO2 88% on room air). What is the most appropriate immediate treatment?