A 70-year-old with COPD on LAMA/LABA has two exacerbations in the past year requiring steroids. Blood eosinophils 360/µL. Non-smoker now. Which mainte...

Question

A 70-year-old with COPD on LAMA/LABA has two exacerbations in the past year requiring steroids. Blood eosinophils 360/µL. Non-smoker now. Which maintenance escalation aligns with guidance?

Accepted Answer

Escalate to triple therapy (ICS/LABA/LAMA)

Answer

Continue LAMA/LABA; avoid ICS regardless of eosinophils

Answer

Switch to LABA/ICS only

Answer

Add theophylline

Answer

Add chronic oral prednisone 5 mg daily

us-abfm MCQ (SBA): COPD Maintenance Escalation

A 70-year-old with COPD on LAMA/LABA has two exacerbations in the past year requiring steroids. Blood eosinophils 360/µL. Non-smoker now. Which maintenance escalation aligns with guidance?