A 64-year-old with type 2 diabetes and eGFR 28 mL/min/1.73 m² asks about continuing metformin. What do current CKD guidance suggest?...

Question

A 64-year-old with type 2 diabetes and eGFR 28 mL/min/1.73 m² asks about continuing metformin. What do current CKD guidance suggest?

Accepted Answer

Continue metformin if eGFR ≥30; discontinue if eGFR

Answer

Continue metformin at usual dose regardless of eGFR

Answer

Increase metformin dose to overcome insulin resistance

Answer

Stop metformin if eGFR

Answer

Switch to DPP‑4 inhibitor because safer at any eGFR

us-usmle-step-2 MCQ (SBA): Metformin in CKD