A 59-year-old with recurrent gout flares and serum urate 9.0 mg/dL has CKD stage 3a (eGFR 52). Which long‑term approach is recommended?...

Question

A 59-year-old with recurrent gout flares and serum urate 9.0 mg/dL has CKD stage 3a (eGFR 52). Which long‑term approach is recommended?

Accepted Answer

Initiate allopurinol as first‑line ULT with low starting dose and titrate to serum urate

Answer

Probenecid monotherapy as first‑line ULT

Answer

Febuxostat is first‑line only if CKD is present

Answer

Avoid ULT until ≥6 flares per year occur

Answer

Colchicine for flares only; avoid ULT due to CKD

us-abfm MCQ (SBA): Gout