Question

A 66-year-old on apixaban 5 mg twice daily for AF with normal renal function is scheduled for elective open hernia repair (high bleeding risk). What perioperative plan is appropriate?

Accepted Answer

Hold apixaban for 2 days pre‑procedure and resume 48-72 hours after, no bridging

Answer

Continue apixaban through surgery

Answer

Hold apixaban morning of surgery only

Answer

Bridge with therapeutic LMWH after stopping apixaban

Answer

Switch to warfarin a week before surgery

Practice question

A 66-year-old on apixaban 5 mg twice daily for AF with normal renal function is scheduled for elective open hernia repair (high bleeding risk). What perioperative plan is appropriate?