Question

A 56-year-old with COPD exacerbation and frequent exacerbations despite optimized inhalers asks about macrolide prophylaxis. He is a former smoker with QTc 420 ms. Which is appropriate?

Accepted Answer

Consider azithromycin prophylaxis after evaluating risks and hearing/QT monitoring

Answer

Macrolide prophylaxis for all without evaluation

Answer

No role for macrolides

Answer

Start chronic prednisone instead

Answer

Start theophylline instead

Practice question

A 56-year-old with COPD exacerbation and frequent exacerbations despite optimized inhalers asks about macrolide prophylaxis. He is a former smoker with QTc 420 ms. Which is appropriate?